We make simplifications constantly, for everything.
Supercomputers allow us to get answers to things without having to simplify as much, they can be used to more accurately predict weather patterns, visualize the result of protein folding and interactions with other molecules for genetic and drug research, potentially model a brain down to the individual neurotransmissor…
Sometimes a simplified model can be good enough and can predict the state of something in the near future, however the more accurate you want your result or the further into the future you want to look, the less assumptions you will be allowed to make and the more computing power will be required to get every detail just right.
Essentially, anything you can think of that is very important to us and can be broken down into smaller and smaller components, supercomputers are good for that.
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