Taking the long acting antacids for more than two weeks can lead to vitamin B-12 deficiency among other things. This results megaloblastic anemia. The antacids also causes
proteins to be poorly digested which can lead to malnutrition. It can cause calcium deficiency.
In order for most forms of B-12 to be absorbed by the intestines they need to be activated by stomach acid first.
For this reason it’s recommend to take the course of pills in a single bottle, then stop taking for several weeks before starting another bottle, to allow more B-12 to be absorbed.
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