why are pills so intense on the stomach?

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According to google, the maximum dosage of ibuprofen is 3200mg divided into 3 or 4 equal dosages (that’s 800mg every 6 hours). For reference, that is less than the weight of a paperclip. So what makes pills so strong that it’s extrmeley dangerous for a stomach that can literally devour steel to consume more than a paperclip weight of ibuprofen every 6 hours?

And that’s only ibuprofen, i’ve taken others meds which were WAY lower at 80mg max dosage and another one 10mg!

Note: didn’t know what to put as flair since it’s technically medicine or biochem (neither are available) so i chose biology since i’m focusing on an organ

In: Biology

7 Answers

Anonymous 0 Comments

It’s because ibuprofen, and other NSAIDs, work by blocking a pathway that helps protect the stomach from stomach acid. There’s a fine balance of proteins required to keep the stomach full of acid but the stomach lining safe. When you disturb that balance with NSAIDs it leads to gastritis (inflammation of the stomach lining) or have an ulcer (a local breakdown in barrier protection of the stomach).

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