You can buy 200mg in every drugstore in hundred packs but for the 600mg you need a prescription. Is it not the same if I take 3 x 200mg or one 600mg? What’s the reason behind this? For me I can’t make sense of it.
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Because ibuprofen exhibits greater anti-inflammatory effects at higher doses, as opposed to just pain relieving effects at OTC doses. If you need to treat inflammation, you need to take more. The downside is that you get worse side effects with higher doses. Stomach ulcers, swelling/water retention, cardiovascular and kidney issues, etc. are all worse at higher doses. NSAIDs like ibuprofen are actually one of the leading causes of prerenal acute kidney injury. Despite being OTC, certain drugs need to be monitored more closely at higher doses.
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Ok, before this completely derails with bs answers, real talk:
There is no difference between 4 200 mg tabs and 1 800 mg tab. The only difference is the perceived benefit, and a placebo effect. There are a number of trials that prove this. There is no difference in rate of absorption or the effectiveness or length… There are studies that show that anything over 400 mg doesn’t provide any additional benefit, but increases the possibility and severity of side effects.
They don’t make 800 mg tabs over the counter because they can’t anticipate people won’t be dumb and pop 2 or 3 of them at a time, or take it as often as they would 200 mg. Same reason they don’t make 1000 mg tabs of acetaminophen. They can, but they don’t, because people are really irresponsible and don’t read directions.
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