Drugs usually target a certain pathway and receptor in our bodies when we give a drug, we alter or shut that pathway down to get the effect we want. Many pathways do multiple things though. Therefore when you shut down the pathway you get side effects from other things that pathway does. For example ibuprofen (NSAIDs) Block an enzyme called cox1 and cox2. This shuts relieves inflammation and pain but it also inhibits anti-apoptotic signals to gastric mucosa cells which is why once side effect of NSAIDs is stomach ulcers
Latest Answers