Insects don’t have a way to move oxygen through their bodies. Unlike humans, oxygen passively travels into the body through tiny holes (spiracles) and passageways in their bodies. Since there is no mechanism to pump air in and out like lungs, this limits the amount of oxygen that gets to their core.
Vertebrates, OTOH, usually have a circulatory system that carries oxygen in blood through the body. This is usually the limiting factor in any activity, and a good circulatory system allows them to grow very large. The blue whale, for example, has a heart the size of a small car.
Insects do have a circulatory system, but it is only designed to carry water and nutrients, not oxygen, so again, that limits their size
Latest Answers