Other than reuse, as it has already been mentioned, constant exposure to the elements leads to erosion which can break down old buildings. Also, catastrophic weather events like hurricanes, earthquakes, floods, fires, and mudslides can quickly destroy cities especially when no one is there to rebuild them. Other animals can also destroy parts of buildings and lead to things breaking down quicker.
Sometimes we just build right over the old building as well. If you go to older cities in Europe there will often be many different foundations near buildings that are the remnants of old buildings that were torn down and built on top of.
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