Few reasons.
First, when you eat, blood in your body focuses near your digestive system, and those organs are currently working digesting the food you just ate. Due to the lack of blood flow to other parts of your body, you get that fatigued feeling. This feeling is accelerated by the fact that us sitting also screws with our blood flow, making us feel more tired. This is also why a lot of students fall asleep during the class after lunch.
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