Why do we use antagonists to treat depression?

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If depression is caused by an undersupply of a neurotransmitter like serotonin and we want to increase that, why do we use antagonist drugs to treat depression instead of agonists?

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3 Answers

Anonymous 0 Comments

The whole neurotransmitter theory of depression has essentially no evidence backing it up. There’s also no real agreed upon method for why antidepressants work, or whether they’re all that effective in the first place.

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