– Why does body weight matter with certain drugs?

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Wondering why body weight matters with certain drugs. It’s never made sense to me considering that drugs act on receptors in the brain, so I don’t see why body weight would matter if the drug is only affecting the brain receptors

In: Biology

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Anonymous 0 Comments

Body weight matters with all drugs because of bioavailability. Drugs are dosed by weight per kg from the manufacturer. Your BMI or BMA for infants, is what determines the amount of drug you are given based on it’s half-life (how long it’s active/stays in your system), it’s strength, route of administrationand frequency. Your weight directly correlates to the dose to avoid a low dose or an overdose. Also contrary to popular belief pharmacy tech and pharmacists do the dosage calculations for a lot of prescriptions.

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