Why does it seem cis men on TRT need a higher dose than trans men on HRT?

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Whenever I see trans men talk about their dose and levels, the average dose seems to be 60-100mg ~~of~~ weekly to get to 500-1000ng/dL. But when I see cis men (with low testosterone) talking about it, their average dose seems to be 100-200mg weekly to get to 500-1000ng/dL. What’s the difference?

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Anonymous 0 Comments

The testosterone given to trans men is called “testosterone undecanoate”. It slowly breaks down in the body over 3-4 weeks. The testosterone often given for TRT is “testosterone cypionate” which breaks down over 3-4 days. If you create a decay curve, you’ll see the average blood serum levels of testosterone is about the same for both.

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