Frisson or music chills is due to a release of dopamine. Dopamine is a neurotransmitter that is basically a reward and pleasure chemical in your brain. It’s also released when you eat, play video games, gamble, take drugs like cocain, and have sex; it makes you feel good. As for causing chills, I suppose it’s due to the release being very sudden and brief whereas other instances of its use (having sex or eating a pizza) are at a lower level but last longer.
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