Why haven’t we come up with a biomarker test for clinical depression yet?
In: Biology
Depression is likely an umbrella term that covers a wide variety of underlying conditions, and we don’t have a well founuded model of what depression is, so don’t really konw what to test for.
In studies there are various markers associated with depression, worse mitocohdrial health, smaller brain volume, worse brain connectivity, lower BDNF levels, etc.(all of which are improved by exercise). But a problem with that is they are hard/expensive/impracticle to test. Then while you can observe associations, those associations might not be strong enough to use as a test.
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