You have 2 copies of (almost) every gene. Sometimes one copy is bad, but that’s fine because you still have one good copy.
Because genes are inherited, people closely related to you will likely have similar mixes of good copies and bad copies.
When you have kids, you pass one copy of each gene to them, and their other copy comes from your mate. If you pass on a bad copy, and your mate is closely related to you, then there’s a higher chance that your kid will end up with 2 bad copies and no good copies of some genes, resulting in defects.
If you don’t know what genes are, they’re basically the “chapters” of your DNA that instruct how to build all the components that make up your body.
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