You are allergic to things that your immune system is already primed to fight. In a sense you have been “vaccinated” to an allergen by prior exposure, and so you mount a fast and intense immune response.
When you get sick more slowly, your immune system has encountered something that it had not learned to fight, and the reactions take a few days to ramp up as it “learns” to first detect and then react to the unfamiliar infection.
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