Weed generally doesn’t have the withdrawal effects because THC is fat soluble. It gets deposited into fat and then when you stop using weed it slowly makes its way back into the bloodstream over time. This means that it basically tapers itself off. It’s also why drug tests can pick up THC weeks later whereas other drugs are gone in a few days.
Hey, I’m no expert but I studied neurons for what it’s worth and wanted to add something.
Dopamine and serotonin are excitatory neurotransmitters, neurons produce a molecule (neuromelanin) to protect themselves from excessive catecholamines (serotonin e dopamine among others) and from metals. So, maybe they are not that great for neurons?
Source, this book: https://www.edisesuniversita.it/area_scientifica/citologia-e-istologia.html
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