The body does not adapt well to not having sex hormones. It needs either a high testosterone or a high oestrogen level to function, and a cis man with low testosterone is low on both.
These two hormones do a lot more than just sex characteristics: they regulate where fat is stored, how muscles are rebuilt, and even how soft cell walls are. They play a part in blood pressure, migraine risk and bone density. And of course, your mood and how your body deals with emotions.
Tl;dr the depression of low testosterone is but a symptom of a whole array of issues caused by too little hormones. Women have oestrogen to fulfil those duties instead.
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