Why some cells can’t undergo mytosis as much as others?

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I watched a video called “What exercise does to your body” by The Institute of Human Anatomy. The host said that heart cells dont undorgo mytosis, and dead ones are replaced by scar tissue, thats why a heart attack is so dangerous. Also, brain damage is permanent for the same reason, and a severe enought stroke is can make one a vegetable for the rest of one’s life. Why those very important cells cant be easilly replaced like ones from bones and skin?

Sorry for any typo, as I’m posting from mobile.

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Anonymous 0 Comments

So, I’m no expert but basically, the brain and heart are both very sensitive to size etc. Mitosis always has the possibility of errors during the replication process as well as mutation, therefore the more replication occurs the more likely there is to be an error or mutation.

Areas of the body most prone to cancers and tumours also tend to be areas that have a lot of mitosis e.g. your skin.

If your heart had a tumour it would massively impact ability to hold pace and if the tumour was internal it could contract blood flow or allow for stagnation and clotting. All of which is very very bad. A heart has enough tissue to give you a standard length of life so long as you do what you can to look after the rest of your health. Therefore the advantages outway the disadvantages.

Similar thing with the brain. We’re still learning to understand the brain but its exact mass, and location of specific cells probably play a massive roll. It wouldn’t hold up to the same kind of stresses things like skin can. You can have too much skin and not die, you can have thin skin or tight skin etc and it’s all pretty much not life threatening. But tumour in the brain, or a glitch in the replication process etc would be a problem.