Think of iso as the sensitivity of a microphone. If you increase it, it can pick smaller sounds but also background noise.
Diaphragm is just a adjustable hole in the lens to allow more or less light. It also affects depth of field.
When taking a landscape photography you want the maximum of the landscape to be sharp, so you increase the F stop number, which make the diaphragme hole smaller. Undesirable effect is that you have less light (issue with night landscapes).
When shooting portrait you generally want a soft background to focus the viewer into the face. You reduce the F stop number, which increases the diameter of the hole in the diaphragm. More light enters and the depth of field is reduced.
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