Here’s a massive over simplification- Think of your body like a computer. Nerves send signals to the brain like a computer keyboard sends inputs to the motherboard. X button input means cold, y input means pain etc. Now plug an interrupter between keyboard and motherboard. Every time you press y, the signal gets blocked, and the pc doesn’t register a button was pressed. The signal was still sent as far as the keyboard is concerned, but since the computer didn’t recieve it, nothing was registered. Some pain killers work similarly. They plug a new chemical compound into the inputs on your brain and stop the pain signal from being recieved. If your brain doesn’t get the pain signal, you don’t feel it.
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