The appetite suppression side effect from Ozempic probably makes the biggest difference in weight loss, at least at the initial low doses. It makes dieting much easier. Some people don’t even consciously go on a diet, but they still lose weight because they eat less due to suppressed appetite.
At a certain dose, another important effect occurs which seems to lower the body’s resistance to caloric reduction. Diets almost always fail because the body fights against them, and takes metabolic steps to make further weight loss difficult. Ozempic seems to reduce that resistance and allows weight loss to continue for a longer period of time.
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