The only reason that it might be a risk for the donor is stress. A lot of autoimmune disorders flair up due to stress (phisycal or mental). With donating blood you are causing stress to the body (now you have to produce more than usual blood cells) which can sometimes trigger an immune response (headaches, fever,). If the situation allows it, and you have autoimune disorders in the family, generally are tired, over worked, stressed out mentally it can be a trigger. Even if you have an autoimmune disorder that is under control its not advisable to donate blood for your sake (may cause flair up, stop the remission) and for the recipients sake.
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