It’s not anything about marijuana per se, but the best answer I can give you is mixing stimuli that act on different neurotransmitters can have compounding effects, like serotonin syndrome, or like the famous DJ screw who died from mixing cocaine, alcohol, and codeine cough syrup.
Marijuana in particular affects your dopamine levels, so combining that with alcohol pronounces the depressant “downer” effects and the naseua. It also throws you “sideways”.
I say there’s “siders”, or disassociatives like DXM, as well as uppers, downers, and hallucinogens.
Marijuana is actually quite hallucinogenic, and when combined with the depressant effects of alcohol I feel a bit “sideways” or disassociated. The street term is “crossfaded”, and it’s actually very harmful for your brain chemistry to do regularly.
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