without prior human use, how is a drug determined safe enough for human clinical trials?
In: Biology
Drugs first go through animal testing before being tested on humans. After that testing is completed successfully, phase I human trials start and are limited to usually 20-100 people and are meant to test for safety and dosage. If phase I is successful, the drug moves on to phases II and III which test for efficacy/side-effects and efficacy/adverse reactions.
There’s also a lot of science going into the development of the drug before animal trials that adds to the calculus of it all.
Latest Answers